Oxford's coronavirus vaccine trial on monkeys shows promise. Scientists at the University of Oxford study found that the experimental vaccine successfully blocked the coronavirus in the monkeys.
A single vaccination dose was effective in preventing damage to the lungs. It induced a humoral and cellular imune response in rhesus macaques. „We observed a significantly reduced viral load in brochoalveolar lavage fluid and respiratory tract tissue of vaccinated animals challenged with SARS-Cov-2 (Covid 19) compared with control animals and no pneumonia was observed in vaccinate rhesus macaques,” researchers said. Also, there was no sign that the vaccine had made the animal more vulnerable.The monkeys share a majority of their genes with humans but there is not guarantee that the results would replicate in people.
Clinical trials with the Oxford vaccine are ongoing in humans. The researchers at Oxford University who have begun testing their potential vaccine against COVID-19 on a small group of human volunteers also hope to expand the tests soon after getting positive results from the initial trial. he potential upcoming vaccine, ChAdOx1 nCoV-19, is based on an adenovirus vaccine vector and the SARS-CoV-2 spike protein. British drugs giant AstraZeneca has struck up a "landmark partnership” with the Oxford University to produce 100 million doses by the end of the year if the traials prove successful.