A RMIT University team found that such molecules were up to 24 times more effective at killing cancer cells than widey used anti-cancer drug cisplatin. In fact, it’s about a promising new class of gold-based drugs that can wipe out the cancer without destroying healthy cells. RMIT’s Molecular Engineering Group co-leader Dr Neda Mirzadeh said the effectiveness of other metal-based drugs is limited due to toxic side effects but „the gold-based molecules we’ve designed are far more selective and stable.” The molecules were evaluated in pre-clinical tests and found to be highly toxic against prostate, breast, cervical, melanoma and colon cancer cells.
Animal trials showed the molecules inhibited tumour growth up to 46.9 per cent compared to 29 per cent with cisplatin. Gold had an ancient history of medical use, particularly in India and China but the methods are not scientifically validated. The next stage of the research including clinical studies must be funded. The research group falls under the umbrella of RMIT’s Center for Advanced Materials and Industrial Chemistry (CAMIC). A study was published in the ‘Chemistry – A European Journal’.