Lupin Pharmaceuticals issued a voluntary recall of some blood pressure medication distributed across the country due to the potential presence of a nitrosamine impurity.It’s about one batch of 20-milligram Quinapril Tablets USP – G102929 – and three batches of 40-milligram Quinapril Tablets USP – G100533, G100534 and G203071. Quinapril is an angiotensin-converting enzyme inhibitor that is used to treat hypertension in order to lower blood pressure. The four lots included in the recall have expiration dates through April 2023, December 2022 and March 2024. Nitrosamines “may increase the risk of cancer if people are exposed to them above acceptable levels over long periods of time,” according to the recall notice.
Nitrosamines are regularly found in meats, dairy products and vegetables and also in water. There haven’t been any illnesses related. Lupin Pharmaceuticals said in the release that wholesalers, distributors, drug chains, mail order pharmacies and supermarkets should “immediately” stop distributing the affected tablets. Over the last couple of years, the FDA has added to its guidance for controlling nitrosamine impurities in some common drugs, including blood pressure and diabetes.