The old vaccine BCG against tuberculosis proved capability to block Covid infection

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It was found that Covid-19 virus could activate latent tuberculosis and this an aspect to consider when evaluating persons at high risk. On the other part, an interesting thing was found and proved by trial: Cedars-Sinai investigators determined that the the BCG antituberculosis vaccine developed a century ago helps to prevent the Covid-19 infection. Researchers tested the blood of more than 6,000 healthcare workers in the Cedars-Sinai Health System. Participants were also asked about their medical and vaccination histories. those with a history of BCG vaccination—about 30% of the total—were significantly less likely to have tested positive for COVID-19 antibodies than those who had never received the BCG vaccine, even if that BCG would not be more effective than the vaccines developed specifically for COVID-19. Other studies tageted participants who had Type 1 diabetes. The resuls were promising in favour of people previously BCG vaccinated. Just 1% of the 96 people who got the BCG shots developed COVID. In several countries, including the Netherland , Greece and Australia, this idea is a subject of study now.

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BCG contains a live, weakened strain of Mycobacterium bovis, a cousin of M. tuberculosis, the microbe that causes TB.The BCG shots are still given to infants in parts of the world that continue to record TB cases. BCG may also increase the ability of the immune system to fight off pathogens other than the TB bacterium, according to clinical and observational studies published over several decades.