A “pen-like” instrument can help in surgery of tumors


When touching the pen to an area of the patient’s body, a drop of water extracts tiny molecules from the patient’s tissue. A spectrometer also tells surgeons whether or not the molecules they’re looking at are healthy tissue or cancerous. In just a matter of seconds, the surgeons can then identify the location of the cancerous tissue that needs to be cut. So it is used in real time during surgery. In their research, scientists also used the device for in vivo cancer diagnosis in mice, which refers to testing on the entire organism, not just on tissue.

The medical new device

Currently, the pen can analyze a 0.06 inch patch of tissue but researchers have already developed pens that can analyze 0.02 inch patches. This is the direction of development. Conventional methods for histopathologic tissue diagnosis are labor- and time-intensive and can delay decision-making during diagnostic and therapeutic procedures. The authors of this research are: Jialing Zhang, John Rector,John Q. Lin, Jonathan H. Young,Marta Sans,Nitesh Katta, Noah Giese1, Wendong Yu, Chandandeep Nagi, James Suliburk, Jinsong Liu, Alena Bensussan, Rachel J. DeHoog, Kyana Y. Garza, Benjamin Ludolph, Anna G. Sorace, Anum Syed, Aydin Zahedivash, Thomas E. Milner and Livia S. Eberlin.


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