“Whether you are being prescribed painkillers like ibuprofen, or buying them over the counter, people must be made aware of the risk,” Dr Mike Knapton, associate medical director at the British Heart Foundation, said. At te same time, there are good news too: “People taking over-the-counter NSAIDs should not be concerned by this research if they are taking the medicine occasionally for short periods and according to the on-pack instructions,” said John Smith, chief executive of the Proprietary Association of Great Britain, which represents makers of over-the-counter medicine. Not at least some painkiller methods of the alternative medicine should be considered before using drugs with known potentially dangerous adjacent effects.