A trial found taking anastrozole for five years cut the risk of contracting the disease by 53 per cent among that high-risk group. The drug was also found not to have side effects.Queen Mary University and Cancer Research UK consider this “one step closer to creating a future without breast cancer”. Baroness Delyth Morgan of Breast Cancer Now told the Daily Mail: “Studies have shown anastrozole cuts the risk of the disease in post-menopausal women by more than 50 per cent in the first five years, and, crucially,it has fewer side effects than other preventive options such as tamoxifen and raloxifene. However, bone weakness has been associated with anastrozole which induced osteoporosis. Acne, constricted pupils and water retention have also been attributed with use of this anti-estrogen.
The drug was also tested in men. Study data suggest dosages of 0.5 mg to 1 mg a day reduce serum estradiol which is known to favorize benign prostatic hyperplasia, gynecomastia, and symptoms of hypogonadism.