The study, based on previous researches which targeted over 300,000 women, found that the women who had earlier onset of menopause had 50 percent increased risk of developing coronary heart disease, which can lead to chest pain and heart attack as plaque accumulates on the wall of the arteries. Knowing this, those who reach menopause early should also be screened for other medical conditions such as diabetes, hypertension and hyperlipidemia so these disorders can be treated as early as possible. The reason why early menopause is tied to increased health risks is not clear. One in 10 women reaches natural menopause at 45 years old, this is premature menopause. Menopause can also be considered as a sign of overall aging. Those women who enter menopause early should consider hormone therapy if they are eligible to manage symptoms and protect vascular and bone health. Researchers from Netherlands published the study in JAMA Cardiology on Sept. 14.